Reactome | WNT ligands traffic to the Golgi

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WNT ligands traffic to the Golgi Show undefined attributes

category	omitted
compartment	[Compartment:17963] Golgi lumen [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10507197
displayName	WNT ligands traffic to the Golgi
eventOf	[Pathway:R-SSC-3238698] WNT ligand biogenesis and trafficking - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-3247840] WLS binds WNT ligands in the Golgi - Sus scrofa
inferredFrom	[BlackBoxEvent:R-HSA-3247837] WNT ligands traffic to the Golgi - Homo sapiens
input	[CandidateSet:R-SSC-3238374] palmitoleyl-N-glycosylated WNTs [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	WNT ligands traffic to the Golgi
output	[CandidateSet:R-SSC-3247824] palmitoleyl-N-glycosylated WNTs [Golgi lumen]
regulatedBy	[PositiveRegulation:10507198] Positive regulation by 'TMED5 [endoplasmic reticulum membrane]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-3247837
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-3238698] WNT ligand biogenesis and trafficking
(precedingEvent)	[Reaction:R-SSC-3247840] WLS binds WNT ligands in the Golgi
(inferredTo)	[BlackBoxEvent:R-HSA-3247837] WNT ligands traffic to the Golgi

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