Reactome | BORA binds PLK1 and AURKA

Schema > Reaction > Entries

BORA binds PLK1 and AURKA Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10506131
displayName	BORA binds PLK1 and AURKA
eventOf	[Pathway:R-SSC-2565942] Regulation of PLK1 Activity at G2/M Transition - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-3000310] AURKA phosphorylates PLK1 - Sus scrofa
inferredFrom	[Reaction:R-HSA-3000319] BORA binds PLK1 and AURKA - Homo sapiens
input	[Complex:R-SSC-3000302] Centrosome:p-T288-AURKA [cytosol] [EntityWithAccessionedSequence:R-SSC-4086411] phospho-BORA [cytosol] [EntityWithAccessionedSequence:R-SSC-164603] PLK1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	BORA binds PLK1 and AURKA
output	[Complex:R-SSC-3000313] Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol]
precedingEvent	[Reaction:R-SSC-4086410] CCNB:CDK1 phosphorylates BORA - Sus scrofa [Reaction:R-SSC-2574840] AJUBA facilitates AURKA autophosphorylation - Sus scrofa [Reaction:R-SSC-9929532] CCNA:CDK1 phosphorylates BORA - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-3000319
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2565942] Regulation of PLK1 Activity at G2/M Transition
(precedingEvent)	[Reaction:R-SSC-3000310] AURKA phosphorylates PLK1
(inferredTo)	[Reaction:R-HSA-3000319] BORA binds PLK1 and AURKA