Reactome | spherical HDL [extracellular region]

Schema > Complex > Entries

spherical HDL [extracellular region] Show undefined attributes

candidateOf	[CandidateSet:R-SSC-9707486] LDL,HDL [extracellular region] - Sus scrofa
compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-SSC-174643] spherical HDL:apoC-II:apoC-III:apoE [extracellular region] - Sus scrofa [Complex:R-SSC-8858255] HDLBP:HDL [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Sus scrofa [Reaction:R-SSC-8858252] HDLBP binds HDL - Sus scrofa [Reaction:R-SSC-174690] TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III - Sus scrofa [Reaction:R-SSC-266315] LCAT + spherical HDL <=> LCAT:spherical HDL complex - Sus scrofa [Reaction:R-SSC-349637] spherical HDL and SR-BI receptor form a complex at the cell surface - Sus scrofa [Reaction:R-SSC-266303] Spherical HDL binds C and E apolipoproteins - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10461433
displayName	spherical HDL [extracellular region]
hasComponent	4 × [EntityWithAccessionedSequence:R-SSC-174720] APOA1 [extracellular region] 160 × [SimpleEntity:R-ALL-171076] CHEST [extracellular region] 40 × [SimpleEntity:R-ALL-171149] CHOL [extracellular region] 140 × [SimpleEntity:R-ALL-171066] PL [extracellular region] 20 × [SimpleEntity:R-ALL-171126] TAGs [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-265523] spherical HDL [extracellular region] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-SSC-2197637] Ligands of SCARB1 [extracellular region] - Sus scrofa [DefinedSet:R-SSC-2187232] Ligands of CD36 [extracellular region] - Sus scrofa
name	spherical HDL
producedByEvent	[BlackBoxEvent:R-SSC-2395784] Nascent CMs transform into mature CMs - Sus scrofa [Reaction:R-SSC-266310] LCAT:spherical HDL complex <=> LCAT + spherical HDL - Sus scrofa [Reaction:R-SSC-174660] nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-265523
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(output)	[BlackBoxEvent:R-SSC-2395784] Nascent CMs transform into mature CMs [Reaction:R-SSC-266310] LCAT:spherical HDL complex <=> LCAT + spherical HDL [Reaction:R-SSC-174660] nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron
(input)	[Reaction:R-SSC-8858252] HDLBP binds HDL [Reaction:R-SSC-174690] TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III [Reaction:R-SSC-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids [Reaction:R-SSC-266303] Spherical HDL binds C and E apolipoproteins [Reaction:R-SSC-266315] LCAT + spherical HDL <=> LCAT:spherical HDL complex [Reaction:R-SSC-349637] spherical HDL and SR-BI receptor form a complex at the cell surface
(hasComponent)	[Complex:R-SSC-8858255] HDLBP:HDL [plasma membrane] [Complex:R-SSC-174769] spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III [extracellular region] [Complex:R-SSC-266308] LCAT:spherical HDL complex [extracellular region] [Complex:R-SSC-174643] spherical HDL:apoC-II:apoC-III:apoE [extracellular region]
(hasMember)	[DefinedSet:R-SSC-2197637] Ligands of SCARB1 [extracellular region] [DefinedSet:R-SSC-2187232] Ligands of CD36 [extracellular region]
(hasCandidate)	[CandidateSet:R-SSC-9707486] LDL,HDL [extracellular region]
(inferredTo)	[Complex:R-HSA-265523] spherical HDL [extracellular region]

© 2026 Reactome

Cite Us!