Reactome | Nascent CMs transform into mature CMs

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Nascent CMs transform into mature CMs Show undefined attributes

category	omitted
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10503474
displayName	Nascent CMs transform into mature CMs
eventOf	[Pathway:R-SSC-975634] Retinoid metabolism and transport - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-2395768] LPL hydrolyses TGs from mature CMs - Sus scrofa
goBiologicalProcess	[GO_BiologicalProcess:357879] chylomicron remodeling
inferredFrom	[BlackBoxEvent:R-HSA-2395784] Nascent CMs transform into mature CMs - Homo sapiens
input	[Complex:R-SSC-2395765] nascent CM:atREs [extracellular region] [Complex:R-SSC-174643] spherical HDL:apoC-II:apoC-III:apoE [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Nascent CMs transform into mature CMs
output	[Complex:R-SSC-2395771] mature CM:atREs [extracellular region] [Complex:R-SSC-265523] spherical HDL [extracellular region]
precedingEvent	[BlackBoxEvent:R-SSC-2187332] Cytosolic CMs translocate to extracellular region - Sus scrofa
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-2395784
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-975634] Retinoid metabolism and transport
(precedingEvent)	[Reaction:R-SSC-2395768] LPL hydrolyses TGs from mature CMs
(inferredTo)	[BlackBoxEvent:R-HSA-2395784] Nascent CMs transform into mature CMs

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