Reactome | SHC-related events triggered by IGF1R

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SHC-related events triggered by IGF1R Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10557991
displayName	SHC-related events triggered by IGF1R
eventOf	[Pathway:R-SSC-2428924] IGF1R signaling cascade - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-2404195] IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 - Sus scrofa [Reaction:R-SSC-2404193] IGF1R phosphorylates SHC1 - Sus scrofa [Reaction:R-SSC-5686072] p-3Y-SHC1 dissociates from IGF1R - Sus scrofa [Reaction:R-SSC-5686073] GRB2-1:SOS1 binds p-3Y-SHC1 - Sus scrofa
inferredFrom	[Pathway:R-HSA-2428933] SHC-related events triggered by IGF1R - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SHC-related events triggered by IGF1R
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-2428933
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2428924] IGF1R signaling cascade
(inferredTo)	[Pathway:R-HSA-2428933] SHC-related events triggered by IGF1R

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