Reactome | Recruitment of clathrin coated vesicle by Ii

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Recruitment of clathrin coated vesicle by Ii Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10501350
displayName	Recruitment of clathrin coated vesicle by Ii
eventOf	[Pathway:R-SSC-2132295] MHC class II antigen presentation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SSC-2130725] Internalization of MHC II:Ii clathrin coated vesicle - Sus scrofa
inferredFrom	[Reaction:R-HSA-2130640] Recruitment of clathrin coated vesicle by Ii - Homo sapiens
input	[Complex:R-SSC-177505] Clathrin:AP-2 complex [plasma membrane] [Complex:R-SSC-2130467] MHC class II alpha/beta/Ii nonamer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Recruitment of clathrin coated vesicle by Ii
output	[Complex:R-SSC-2130309] Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane]
precedingEvent	[BlackBoxEvent:R-SSC-2130500] Insertion of MHC II:Ii complex in to the plasma membrane - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-2130640
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2132295] MHC class II antigen presentation
(precedingEvent)	[BlackBoxEvent:R-SSC-2130725] Internalization of MHC II:Ii clathrin coated vesicle
(inferredTo)	[Reaction:R-HSA-2130640] Recruitment of clathrin coated vesicle by Ii

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