Reactome | Clathrin:AP-2 complex [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-2130309] Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] - Sus scrofa [Complex:R-SSC-392743] L1:AP-2 Clathrin complex [clathrin-coated endocytic vesicle] - Sus scrofa [Complex:R-SSC-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-2130640] Recruitment of clathrin coated vesicle by Ii - Sus scrofa [Reaction:R-SSC-6784735] PCSK9:LDLR bind to Clathrin - Sus scrofa [Reaction:R-SSC-8855131] VLDLR:PCSK9 binds Clathrin-coated vesicles - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10461968
displayName	Clathrin:AP-2 complex [plasma membrane]
hasComponent	[Complex:R-SSC-177480] AP-2 complex [plasma membrane] [Complex:R-SSC-177482] Clathrin [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-177505] Clathrin:AP-2 complex [plasma membrane] - Homo sapiens
maxDepth	4
name	Clathrin:AP-2 complex
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-177505
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-2130640] Recruitment of clathrin coated vesicle by Ii [Reaction:R-SSC-6784735] PCSK9:LDLR bind to Clathrin [Reaction:R-SSC-8855131] VLDLR:PCSK9 binds Clathrin-coated vesicles
(hasComponent)	[Complex:R-SSC-2130309] Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] [Complex:R-SSC-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] [Complex:R-SSC-445005] pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome] [Complex:R-SSC-392743] L1:AP-2 Clathrin complex [clathrin-coated endocytic vesicle] [Complex:R-SSC-6784733] PCSK9:LDLR:Clathrin:AP2 [plasma membrane] [Complex:R-SSC-8855134] VLDL:PCSK9:Clathrin:AP2 [plasma membrane] [Complex:R-SSC-177490] Activated TrkA receptor complex:Clathrin-coated vesicle:Endophilin [plasma membrane]
(inferredTo)	[Complex:R-HSA-177505] Clathrin:AP-2 complex [plasma membrane]

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