Reactome | phospho-FOXO1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-9614572] p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-9614423] 14-3-3 proteins bind AKT-phosphorylated FOXO1 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10469049
displayName	phospho-FOXO1 [cytosol]
endCoordinate	655
hasModifiedResidue	[ModifiedResidue:10465651] O-phospho-L-threonine at 24 (in Homo sapiens) [ModifiedResidue:10465652] O-phospho-L-serine at 256 (in Homo sapiens) [ModifiedResidue:10465653] O-phospho-L-serine at 319 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-211158] p-T24,S256,S319-FOXO1 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-SSC-9614416] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4 [cytosol] - Sus scrofa
name	phospho-FOXO1 p-T24,S256,S319-FOXO1 F1RME6
producedByEvent	[Reaction:R-SSC-211178] Phosphorylated FOXO1A is excluded from the nucleus - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:F1RME6] UniProt:F1RME6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-211158
startCoordinate	1

(output)	[Reaction:R-SSC-211178] Phosphorylated FOXO1A is excluded from the nucleus
(input)	[Reaction:R-SSC-9614423] 14-3-3 proteins bind AKT-phosphorylated FOXO1
(hasComponent)	[Complex:R-SSC-9614572] p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol]
(hasMember)	[DefinedSet:R-SSC-9614416] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-211158] p-T24,S256,S319-FOXO1 [cytosol]

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