Reactome | Removal of siRNA passenger strand

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10500818
displayName	Removal of siRNA passenger strand
eventOf	[Pathway:R-SSC-426486] Small interfering RNA (siRNA) biogenesis - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-2106615] Removal of siRNA passenger strand - Homo sapiens
input	[DefinedSet:R-SSC-6789260] TARBP2,PRKRA:DICER1:Pre-RISC (siRNA) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Removal of siRNA passenger strand
output	[DefinedSet:R-SSC-6789257] TARBP2,PRKRA:DICER1:RISC (siRNA) [cytosol]
precedingEvent	[BlackBoxEvent:R-SSC-2106625] Duplex siRNA is loaded into Argonaute - Sus scrofa
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-2106615
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-426486] Small interfering RNA (siRNA) biogenesis
(inferredTo)	[BlackBoxEvent:R-HSA-2106615] Removal of siRNA passenger strand

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