Reactome | CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain

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CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain Show undefined attributes

catalystActivity	[CatalystActivity:10500158] N-acetylglucosamine 6-O-sulfotransferase activity of CHST2,3,5,6 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10500160
displayName	CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain
eventOf	[Pathway:R-SSC-2022854] Keratan sulfate biosynthesis - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-2046175] CHST1 transfers sulfate to Gal on keratan chain - Sus scrofa
inferredFrom	[Reaction:R-HSA-2046222] CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain - Homo sapiens
input	[DefinedSet:R-SSC-2046203] Keratan(4)-PG [Golgi lumen] [SimpleEntity:R-ALL-741440] PAPS [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain Sulfation of GlcNAc residues on Keratan-PG forms KSPG
output	[SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [DefinedSet:R-SSC-2046166] KSPG(1) [Golgi lumen] [SimpleEntity:R-ALL-742343] PAP [Golgi lumen]
precedingEvent	[Reaction:R-SSC-2046285] ST3GAL1-4,6 optionally cap keratan chain - Sus scrofa [Reaction:R-SSC-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-2046222
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2022854] Keratan sulfate biosynthesis
(precedingEvent)	[Reaction:R-SSC-2046175] CHST1 transfers sulfate to Gal on keratan chain
(inferredTo)	[Reaction:R-HSA-2046222] CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain

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