Reactome | DSPGs are secreted

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DSPGs are secreted Show undefined attributes

category	omitted
compartment	[Compartment:17963] Golgi lumen [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10498129
displayName	DSPGs are secreted
eventOf	[Pathway:R-SSC-2022923] DS-GAG biosynthesis - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SSC-2022056] DSPG and CSPG translocate to the lysosome for degradation - Sus scrofa
goBiologicalProcess	[GO_BiologicalProcess:939] protein secretion
inferredFrom	[BlackBoxEvent:R-HSA-2022065] DSPGs are secreted - Homo sapiens
input	[DefinedSet:R-SSC-2065267] DSPGs [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	DSPGs are secreted
output	[DefinedSet:R-SSC-2065240] DSPGs [extracellular region]
precedingEvent	[Reaction:R-SSC-2022052] DSE converts GlcA to IdoA - Sus scrofa [Reaction:R-SSC-2022061] Dermatan sulfate can be further sulfated on position 2 of iduronate - Sus scrofa [Reaction:R-SSC-2022063] CHST14 transfers SO4(2-) to GalNAc in dermatan or DS - Sus scrofa [Reaction:R-SSC-9941312] CHST15 transfers sulfate to (6-)GalNAc-4-sulfate - Sus scrofa
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-2022065
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2022923] DS-GAG biosynthesis
(precedingEvent)	[BlackBoxEvent:R-SSC-2022056] DSPG and CSPG translocate to the lysosome for degradation
(inferredTo)	[BlackBoxEvent:R-HSA-2022065] DSPGs are secreted