Reactome | Dermatan sulfate can be further sulfated on position 2 of iduronate

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Dermatan sulfate can be further sulfated on position 2 of iduronate Show undefined attributes

catalystActivity	[CatalystActivity:10498080] sulfotransferase activity of UST [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10498082
displayName	Dermatan sulfate can be further sulfated on position 2 of iduronate
eventOf	[Pathway:R-SSC-2022923] DS-GAG biosynthesis - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-2022063] CHST14 transfers SO4(2-) to GalNAc in dermatan or DS - Sus scrofa [BlackBoxEvent:R-SSC-2022065] DSPGs are secreted - Sus scrofa
inferredFrom	[Reaction:R-HSA-2022061] Dermatan sulfate can be further sulfated on position 2 of iduronate - Homo sapiens
input	[DefinedSet:R-SSC-2065135] D4S-PGs [Golgi lumen] [SimpleEntity:R-ALL-741440] PAPS [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Dermatan sulfate can be further sulfated on position 2 of iduronate
output	[DefinedSet:R-SSC-2065145] D2,4(S)2-PG [Golgi lumen] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-742343] PAP [Golgi lumen]
precedingEvent	[Reaction:R-SSC-2022063] CHST14 transfers SO4(2-) to GalNAc in dermatan or DS - Sus scrofa [Reaction:R-SSC-2022052] DSE converts GlcA to IdoA - Sus scrofa [Reaction:R-SSC-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-2022061
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2022923] DS-GAG biosynthesis
(precedingEvent)	[BlackBoxEvent:R-SSC-2022065] DSPGs are secreted [Reaction:R-SSC-2022063] CHST14 transfers SO4(2-) to GalNAc in dermatan or DS
(inferredTo)	[Reaction:R-HSA-2022061] Dermatan sulfate can be further sulfated on position 2 of iduronate

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