Reactome | phospho-MAPK8 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10468366] JUN kinase activity of p-T,Y-MAPK8 [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-SSC-193666] Active JNK moves to the nucleus and phosphorylates different transcription factors - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10459410
displayName	phospho-MAPK8 [cytosol]
endCoordinate	427
hasModifiedResidue	[ModifiedResidue:10459297] O-phospho-L-threonine at unknown position [ModifiedResidue:10459298] O4'-phospho-L-tyrosine at unknown position
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-194371] p-T,Y-MAPK8 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-SSC-450226] p-MAPK8,9,10 [cytosol] - Sus scrofa
name	phospho-MAPK8 p-T,Y-MAPK8 A0A5G2Q9X6
producedByEvent	[Reaction:R-SSC-205136] GTP-bound RAC contributes to JNK activation - Sus scrofa [BlackBoxEvent:R-SSC-9008043] MAPK8 phosphorylation - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:A0A5G2Q9X6] UniProt:A0A5G2Q9X6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-194371
startCoordinate	1

(physicalEntity)	[CatalystActivity:10468366] JUN kinase activity of p-T,Y-MAPK8 [cytosol]
(output)	[Reaction:R-SSC-205136] GTP-bound RAC contributes to JNK activation [BlackBoxEvent:R-SSC-9008043] MAPK8 phosphorylation
(input)	[Reaction:R-SSC-193666] Active JNK moves to the nucleus and phosphorylates different transcription factors
(hasMember)	[DefinedSet:R-SSC-450226] p-MAPK8,9,10 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-194371] p-T,Y-MAPK8 [cytosol]

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