Reactome | Mature NOTCH heterodimer traffics to the plasma membrane

Schema > BlackBoxEvent > Entries

Mature NOTCH heterodimer traffics to the plasma membrane Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10496533
displayName	Mature NOTCH heterodimer traffics to the plasma membrane
eventOf	[Pathway:R-SSC-1912420] Pre-NOTCH Processing in Golgi - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-1912382] Mature NOTCH heterodimer traffics to the plasma membrane - Homo sapiens
input	[Complex:R-SSC-157054] NOTCH4 [Golgi membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Mature NOTCH heterodimer traffics to the plasma membrane
output	[Complex:R-SSC-157053] NOTCH4 [plasma membrane]
regulatedBy	[NegativeRegulation:10496534] Negative regulation by 'TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-1912382
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-1912420] Pre-NOTCH Processing in Golgi
(inferredTo)	[BlackBoxEvent:R-HSA-1912382] Mature NOTCH heterodimer traffics to the plasma membrane

Cite Us!