Reactome | EPS15:HGS:STAM [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-8875489] HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM) [plasma membrane] - Sus scrofa [Complex:R-SSC-182936] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] - Sus scrofa [Complex:R-SSC-8867034] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-8875490] EPS15 and HGS bind ubiquitinated MET - Sus scrofa [Reaction:R-SSC-8867044] EGFR binds EPS15, EPN1, EPS15L1 - Sus scrofa [Reaction:R-SSC-183072] EGFR non-clathrin mediated endocytosis - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10462307
displayName	EPS15:HGS:STAM [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-SSC-182920] EPS15 [cytosol] [EntityWithAccessionedSequence:R-SSC-182954] HGS [cytosol] [DefinedSet:R-SSC-182929] STAM [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-182947] EPS15:HGS:STAM [cytosol] - Homo sapiens
maxDepth	3
name	EPS15:HGS:STAM
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-182947
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-8875490] EPS15 and HGS bind ubiquitinated MET [Reaction:R-SSC-8867044] EGFR binds EPS15, EPN1, EPS15L1 [Reaction:R-SSC-183072] EGFR non-clathrin mediated endocytosis
(hasComponent)	[Complex:R-SSC-8875489] HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM) [plasma membrane] [Complex:R-SSC-8867034] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] [Complex:R-SSC-182936] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] [Complex:R-SSC-182961] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane]
(inferredTo)	[Complex:R-HSA-182947] EPS15:HGS:STAM [cytosol]

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