Reactome | EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10462430
displayName	EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane]
hasComponent	[Complex:R-SSC-182960] EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] [Complex:R-SSC-182967] Ub-p-Y53/55-SPRY1/2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-182939] EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] - Homo sapiens
maxDepth	5
name	EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2
producedByEvent	[Reaction:R-SSC-183051] CBL ubiquitinates Sprouty - Sus scrofa [Reaction:R-SSC-183089] CBL binds and ubiquitinates phosphorylated Sprouty - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-182939
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-SSC-183051] CBL ubiquitinates Sprouty [Reaction:R-SSC-183089] CBL binds and ubiquitinates phosphorylated Sprouty
(inferredTo)	[Complex:R-HSA-182939] EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane]

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