Reactome | phospho-NFKBIA [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-209535] Ubiquitinated phospho-IkB [cytosol] - Sus scrofa [Complex:R-SSC-1168600] NF-KappaB p50:p50:p-IKBA [cytosol] - Sus scrofa [Complex:R-SSC-206877] NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-209536] IkB is ubiquitinated and degraded - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10459364
displayName	phospho-NFKBIA [cytosol]
endCoordinate	317
hasModifiedResidue	[ModifiedResidue:10459361] O-phospho-L-serine at 32 (in Homo sapiens) [ModifiedResidue:10459362] O-phospho-L-serine at 36 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-177677] p-S32,S36-NFKBIA [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-SSC-177678] Phospho-NF-kappaB Inhibitor [cytosol] - Sus scrofa [DefinedSet:R-SSC-1168607] p-IKB alpha,beta,epsilon [cytosol] - Sus scrofa
name	phospho-NFKBIA p-S32,S36-NFKBIA Q08353
producedByEvent	[Reaction:R-SSC-209087] IKBA is phosphorylated by Phospho IKKB kinase - Sus scrofa [Reaction:R-SSC-193705] IKKbeta phosphorylates IkB causing NF-kB to dissociate - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:Q08353] UniProt:Q08353
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-177677
startCoordinate	1

(hasComponent)	[Complex:R-SSC-1168600] NF-KappaB p50:p50:p-IKBA [cytosol] [Complex:R-SSC-209535] Ubiquitinated phospho-IkB [cytosol] [Complex:R-SSC-5607671] p-S32,36-IkB-alpha:NF-kB complex [cytosol] [Complex:R-SSC-206877] NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol]
(hasMember)	[DefinedSet:R-SSC-1168607] p-IKB alpha,beta,epsilon [cytosol] [DefinedSet:R-SSC-177678] Phospho-NF-kappaB Inhibitor [cytosol]
(input)	[Reaction:R-SSC-209536] IkB is ubiquitinated and degraded
(output)	[Reaction:R-SSC-193705] IKKbeta phosphorylates IkB causing NF-kB to dissociate [Reaction:R-SSC-209087] IKBA is phosphorylated by Phospho IKKB kinase
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-177677] p-S32,S36-NFKBIA [cytosol]

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