Reactome | Phosphorylation of the APC/C

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10556575
displayName	Phosphorylation of the APC/C
eventOf	[Pathway:R-SSC-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:3446115] regulation of mitotic cell cycle phase transition
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-174119] Free APC/C phosphorylated by Plk1 - Sus scrofa [Reaction:R-SSC-174132] Free APC/C phosphorylated by Cyclin B:Cdc2 - Sus scrofa
inferredFrom	[Pathway:R-HSA-176412] Phosphorylation of the APC/C - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Phosphorylation of the APC/C
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-176412
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
(inferredTo)	[Pathway:R-HSA-176412] Phosphorylation of the APC/C

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