Reactome | Phosphorylation of the APC/C

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Phosphorylation of the APC/C Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:176411] Matthews, L, 2006-03-07 23:42:05
crossReference	[DatabaseIdentifier:12819491] BioModels Database:BIOMD0000000186 [DatabaseIdentifier:12819493] BioModels Database:BIOMD0000000187
dbId	176412
displayName	Phosphorylation of the APC/C
eventOf	[Pathway:R-HSA-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:3446115] regulation of mitotic cell cycle phase transition
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-174119] Free APC/C phosphorylated by Plk1 - Homo sapiens [Reaction:R-HSA-174132] Free APC/C phosphorylated by Cyclin B:Cdc2 - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:174245] Mitotic regulation of the APC activator proteins CDC20 and CDH1
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Phosphorylation of the APC/C
orthologousEvent	[Pathway:R-DDI-176412] Phosphorylation of the APC/C - Dictyostelium discoideum [Pathway:R-DME-176412] Phosphorylation of the APC/C - Drosophila melanogaster [Pathway:R-GGA-176412] Phosphorylation of the APC/C - Gallus gallus [Pathway:R-XTR-176412] Phosphorylation of the APC/C - Xenopus tropicalis [Pathway:R-DRE-176412] Phosphorylation of the APC/C - Danio rerio [Pathway:R-SSC-176412] Phosphorylation of the APC/C - Sus scrofa [Pathway:R-BTA-176412] Phosphorylation of the APC/C - Bos taurus [Pathway:R-CFA-176412] Phosphorylation of the APC/C - Canis familiaris [Pathway:R-RNO-176412] Phosphorylation of the APC/C - Rattus norvegicus [Pathway:R-MMU-176412] Phosphorylation of the APC/C - Mus musculus
releaseDate	2006-04-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:177300] Peters, JM, 2006-03-27 22:55:09
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-176412
summation	[Summation:176410] Phosphorylation of APC subunits is required for Cdc20 mediat...

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[Pathway:R-HSA-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins