Reactome | chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols

Schema > Reaction > Entries

chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols Show undefined attributes

catalystActivity	[CatalystActivity:10461499] lipoprotein lipase activity of GPIHBP1:HSPG:LPL dimer [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10461505
displayName	chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols
eventOf	[Pathway:R-SSC-8963901] Chylomicron remodeling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-174690] TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III - Sus scrofa
inferredFrom	[Reaction:R-HSA-174757] chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols - Homo sapiens
input	[Complex:R-SSC-174697] chylomicron [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols
output	50 × [SimpleEntity:R-ALL-174675] DAGs [extracellular region] 50 × [SimpleEntity:R-ALL-174602] LCFAs [extracellular region] [Complex:R-SSC-174798] TG-depleted chylomicron [extracellular region]
precedingEvent	[Reaction:R-SSC-174660] nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron - Sus scrofa [Reaction:R-SSC-8857928] GPIHBP1 binds HSPG:LPL dimer - Sus scrofa
regulatedBy	[PositiveRegulation:10461506] Positive regulation by 'APOC2 [extracellular region]' [NegativeRegulation:10461507] Negative regulation by 'APOC3 [extracellular region]' [PositiveRegulation:10461508] Positive regulation by 'APOA5 [extracellular region]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-174757
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8963901] Chylomicron remodeling
(precedingEvent)	[Reaction:R-SSC-174690] TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III
(inferredTo)	[Reaction:R-HSA-174757] chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols

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