Reactome | C5 [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-SSC-9957443] C5a:vilobelimab [extracellular region] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-9957405] C5a binds C5a inhibitor - Sus scrofa [Reaction:R-SSC-375395] C5a receptor binds C5a anaphylatoxin - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10460906
displayName	C5 [extracellular region]
endCoordinate	751
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-173677] C5a [extracellular region] - Homo sapiens
maxDepth	1
memberOf	[CandidateSet:R-SSC-964782] C5AR2 ligands [extracellular region] - Sus scrofa [DefinedSet:R-SSC-8852810] C3a, C5a [extracellular region] - Sus scrofa
name	C5 C5a A0A287AIM8
producedByEvent	[Reaction:R-SSC-173680] Activation of C5 - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:A0A287AIM8] UniProt:A0A287AIM8
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-173677
startCoordinate	678

(hasMember)	[DefinedSet:R-SSC-8852810] C3a, C5a [extracellular region] [CandidateSet:R-SSC-964782] C5AR2 ligands [extracellular region]
(input)	[Reaction:R-SSC-9957405] C5a binds C5a inhibitor [Reaction:R-SSC-375395] C5a receptor binds C5a anaphylatoxin
(hasComponent)	[Complex:R-SSC-9957443] C5a:vilobelimab [extracellular region] [Complex:R-SSC-375354] C5AR1:C5a [plasma membrane]
(output)	[Reaction:R-SSC-173680] Activation of C5
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-173677] C5a [extracellular region]

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