Reactome | Phosphorylation and activation of eIF4G by activated S6K1

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Phosphorylation and activation of eIF4G by activated S6K1 Show undefined attributes

catalystActivity	[CatalystActivity:10458893] protein serine/threonine kinase activity of p-T389/412-RPS6KB1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10458902
displayName	Phosphorylation and activation of eIF4G by activated S6K1
eventOf	[Pathway:R-SSC-166208] mTORC1-mediated signalling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-165766] Phosphorylation and activation of eIF4G by activated S6K1 - Homo sapiens
input	3 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-SSC-72584] EIF4G1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation and activation of eIF4G by activated S6K1
output	3 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-SSC-165762] phospho-EIF4G1 [cytosol]
precedingEvent	[Reaction:R-SSC-165718] mTORC1 phosphorylation of RPS6KB1 (S6K) - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-165766
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-166208] mTORC1-mediated signalling
(inferredTo)	[Reaction:R-HSA-165766] Phosphorylation and activation of eIF4G by activated S6K1

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