Reactome | Nuclear Pore Complex (NPC) [nuclear envelope]

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Nuclear Pore Complex (NPC) [nuclear envelope] Show undefined attributes

catalystActivities	[CatalystActivity:10506148] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10512855] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10495837] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
compartment	[Compartment:13231] nuclear envelope
componentOf	[Complex:R-SSC-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-2990882] CDK1 phosphorylates NUP98 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10452317
displayName	Nuclear Pore Complex (NPC) [nuclear envelope]
hasComponent	8 × [EntityWithAccessionedSequence:R-SSC-157738] AAAS [nuclear envelope] 16 × [EntityWithAccessionedSequence:R-SSC-157750] CEP192 [nuclear envelope] 32 × [EntityWithAccessionedSequence:R-SSC-6805183] NDC1 [nuclear envelope] 32 × [Complex:R-SSC-377883] Nup107-160 complex [cytosol] 8 × [EntityWithAccessionedSequence:R-SSC-157695] NUP153 [nucleoplasm] 16 × [EntityWithAccessionedSequence:R-SSC-157752] NUP188 [nuclear envelope] 16 × [EntityWithAccessionedSequence:R-SSC-157722] NUP210 [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-SSC-157691] NUP214 [cytosol] 16 × [EntityWithAccessionedSequence:R-SSC-157697] NUP42 [cytosol] 32 × [EntityWithAccessionedSequence:R-SSC-157740] NUP50 [nucleoplasm] 32 × [Complex:R-SSC-157712] Nup62 Complex [nuclear envelope] 32 × [EntityWithAccessionedSequence:R-SSC-157753] NUP88 [cytosol] 32 × [Complex:R-SSC-9634183] Nup93 complex [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-SSC-2990912] NUP98 [nuclear envelope] 16 × [DefinedSet:R-SSC-6805169] POM121 [nuclear envelope] 48 × [EntityWithAccessionedSequence:R-SSC-157718] RAE1 [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-SSC-157703] RANBP2 [cytosol] 16 × [EntityWithAccessionedSequence:R-SSC-157692] TPR [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope] - Homo sapiens
isRequired	[Requirement:10452508] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
maxDepth	4
name	Nuclear Pore Complex (NPC)
positivelyRegulates	[Requirement:10452508] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
producedByEvent	[Reaction:R-SSC-75098] mRNP complex dissociates from cytosolic face of NPC - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-157689
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(physicalEntity)	[CatalystActivity:10506148] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10512855] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10495837] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
(input)	[Reaction:R-SSC-2990882] CDK1 phosphorylates NUP98
(output)	[Reaction:R-SSC-75098] mRNP complex dissociates from cytosolic face of NPC
(hasComponent)	[Complex:R-SSC-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] [Complex:R-SSC-159259] NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol]
(regulator)	[Requirement:10452508] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
(inferredTo)	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope]

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