Reactome | Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS

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Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS Show undefined attributes

catalystActivity	[CatalystActivity:10493622] serine-type endopeptidase activity of MMP1, 3, 7, 12, 13, 19, CTSS [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10493624
displayName	Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS
eventOf	[Pathway:R-SSC-1474228] Degradation of the extracellular matrix - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1566981] Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS - Homo sapiens
input	[Polymer:R-SSC-2327729] Fibronectin matrix [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS
output	[Polymer:R-SSC-2533900] Cleaved fibronectin matrix [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-1566981
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-1474228] Degradation of the extracellular matrix
(inferredTo)	[Reaction:R-HSA-1566981] Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS

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