Reactome | 1-acyl LPE is acylated to PE by LPEAT

Schema > Reaction > Entries

1-acyl LPE is acylated to PE by LPEAT Show undefined attributes

catalystActivity	[CatalystActivity:10492543] 1-acylglycerol-3-phosphate O-acyltransferase activity of LPEAT [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10492545
displayName	1-acyl LPE is acylated to PE by LPEAT
eventOf	[Pathway:R-SSC-1482839] Acyl chain remodelling of PE - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-1483174] PE is methylated to PC by PEMT - Sus scrofa [Reaction:R-SSC-1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] - Sus scrofa [Reaction:R-SSC-1482828] PE is hydrolyzed to 2-acyl LPE by PLA2[4] - Sus scrofa [Reaction:R-SSC-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3] - Sus scrofa [Reaction:R-SSC-1483089] PE is converted to PS by PTDSS2 - Sus scrofa
inferredFrom	[Reaction:R-HSA-1482667] 1-acyl LPE is acylated to PE by LPEAT - Homo sapiens
input	[SimpleEntity:R-ALL-1498738] 1-acyl LPE [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	1-acyl LPE is acylated to PE by LPEAT
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1500581] PE [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-SSC-1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] - Sus scrofa [Reaction:R-SSC-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3] - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-1482667
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-SSC-1483174] PE is methylated to PC by PEMT [Reaction:R-SSC-1483089] PE is converted to PS by PTDSS2 [Reaction:R-SSC-1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] [Reaction:R-SSC-1482828] PE is hydrolyzed to 2-acyl LPE by PLA2[4] [Reaction:R-SSC-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3]
(hasEvent)	[Pathway:R-SSC-1482839] Acyl chain remodelling of PE
(inferredTo)	[Reaction:R-HSA-1482667] 1-acyl LPE is acylated to PE by LPEAT