Reactome | Mitochondrial protein import

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Mitochondrial protein import Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:70616] mitochondrial inner membrane [Compartment:17927] mitochondrial intermembrane space [Compartment:5460] mitochondrial matrix [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10557897
displayName	Mitochondrial protein import
eventOf	[TopLevelPathway:R-SSC-9609507] Protein localization - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:422648] protein localization to mitochondrion
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-SSC-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Sus scrofa [BlackBoxEvent:R-SSC-8986181] PITRM1 proteolyzes mitochondrial targeting peptides (presequences) - Sus scrofa
inferredFrom	[Pathway:R-HSA-1268020] Mitochondrial protein import - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Mitochondrial protein import
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-1268020
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-SSC-9609507] Protein localization
(hasEncapsulatedEvent)	[Pathway:R-SSC-1592230] Mitochondrial biogenesis [Pathway:R-SSC-9864848] Complex IV assembly
(inferredTo)	[Pathway:R-HSA-1268020] Mitochondrial protein import

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