Reactome | Activation of BAD and translocation to mitochondria

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Activation of BAD and translocation to mitochondria Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10556217
displayName	Activation of BAD and translocation to mitochondria
eventOf	[Pathway:R-SSC-114452] Activation of BH3-only proteins - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:5673453] positive regulation of protein localization to mitochondrion
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-139899] Sequestration of BAD protein by 14-3-3 - Sus scrofa [Reaction:R-SSC-139906] Activation of BAD by calcineurin - Sus scrofa [Reaction:R-SSC-139905] Translocation of activated BAD protein to mitochondria - Sus scrofa [Reaction:R-SSC-139897] BAD displaces tBID from BCL-2 sequestration - Sus scrofa
inferredFrom	[Pathway:R-HSA-111447] Activation of BAD and translocation to mitochondria - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Activation of BAD and translocation to mitochondria
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-111447
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-114452] Activation of BH3-only proteins
(inferredTo)	[Pathway:R-HSA-111447] Activation of BAD and translocation to mitochondria

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