Reactome | CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly

Schema > Reaction > Entries

CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly Show undefined attributes

catalystActivity	[CatalystActivity:11062366] carboxypeptidase activity of CNDP2:2Mn2+ dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11076221
displayName	CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly
eventOf	[Pathway:R-SPO-9753281] Paracetamol ADME - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-9753284] ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-9753632] CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly - Homo sapiens
input	[SimpleEntity:R-ALL-9753680] APAP-CysGly [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly
output	[SimpleEntity:R-ALL-9753653] APAP-Cys [cytosol] [SimpleEntity:R-ALL-29424] Gly [cytosol]
precedingEvent	[Reaction:R-SPO-9753634] GGT dimers hydrolyse APAP-SG - Schizosaccharomyces pombe
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9753632
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-9753281] Paracetamol ADME
(precedingEvent)	[Reaction:R-SPO-9753284] ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region
(inferredTo)	[Reaction:R-HSA-9753632] CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly

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