Reactome | FKBP1A binds tacrolimus

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11075948
displayName	FKBP1A binds tacrolimus
eventOf	[Pathway:R-SPO-2025928] Calcineurin activates NFAT - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9690461] FKBP1A binds tacrolimus - Homo sapiens
input	[EntityWithAccessionedSequence:R-SPO-2026007] fkh1 [cytosol] [ChemicalDrug:R-ALL-9678991] tacrolimus [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FKBP1A binds tacrolimus
output	[Complex:R-SPO-2026019] FKBP1A:tacrolimus [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9690461
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-2025928] Calcineurin activates NFAT
(inferredTo)	[Reaction:R-HSA-9690461] FKBP1A binds tacrolimus

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