Reactome | GAA hydrolyzes lysosomal glycogen

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GAA hydrolyzes lysosomal glycogen Show undefined attributes

catalystActivity	[CatalystActivity:11075145] alpha-glucosidase activity of GAA (70, 76 kDa) [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11075147
displayName	GAA hydrolyzes lysosomal glycogen
eventOf	[Pathway:R-SPO-70221] Glycogen breakdown (glycogenolysis) - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9036727] GAA hydrolyzes lysosomal glycogen - Homo sapiens
input	[Complex:R-SPO-9036726] glycogen-GYG1 dimer [lysosomal lumen] 2 × [SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	GAA hydrolyzes lysosomal glycogen GAA hydrolyzes alpha(1,6) linkages in lysosomal glycogen GAA hydrolyzes alpha(1,4) linkages in lysosomal glycogen
output	2 × [SimpleEntity:R-ALL-1605745] Glc [lysosomal lumen] [Complex:R-SPO-5357533] poly((1,4)-alpha-glucosyl)GYG1 dimer [lysosomal lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9036727
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-70221] Glycogen breakdown (glycogenolysis)
(inferredTo)	[Reaction:R-HSA-9036727] GAA hydrolyzes lysosomal glycogen

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