Reactome | RHOU auto-activates

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RHOU auto-activates Show undefined attributes

catalystActivity	[CatalystActivity:11074856] guanyl-nucleotide exchange factor activity of RHOU:GDP [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11074858
displayName	RHOU auto-activates
eventOf	[Pathway:R-SPO-9013420] RHOU GTPase cycle - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-9018766] RHOU binds effectors at the plasma membrane - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-9018768] RHOU auto-activates - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-SPO-9019557] RHOU:GDP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	RHOU auto-activates
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-SPO-9019560] RHOU:GTP [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9018768
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-9013420] RHOU GTPase cycle
(precedingEvent)	[Reaction:R-SPO-9018766] RHOU binds effectors at the plasma membrane
(inferredTo)	[Reaction:R-HSA-9018768] RHOU auto-activates