Reactome | RHOC GAPs stimulate RHOC GTPase activity

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RHOC GAPs stimulate RHOC GTPase activity Show undefined attributes

catalystActivity	[CatalystActivity:11074710] GTPase activator activity of RHOC GAPs [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11074712
displayName	RHOC GAPs stimulate RHOC GTPase activity
eventOf	[Pathway:R-SPO-9013106] RHOC GTPase cycle - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9013111] RHOC GAPs stimulate RHOC GTPase activity - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-SPO-5665993] RHOA:GTP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	RHOC GAPs stimulate RHOC GTPase activity
output	[SimpleEntity:R-ALL-29372] Pi [cytosol] [Complex:R-SPO-8964174] RHOA:GDP [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9013111
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-9013106] RHOC GTPase cycle
(inferredTo)	[Reaction:R-HSA-9013111] RHOC GAPs stimulate RHOC GTPase activity

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