Reactome | CFTR transits to the plasma membrane

Schema > BlackBoxEvent > Entries

CFTR transits to the plasma membrane Show undefined attributes

category	omitted
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11073010
displayName	CFTR transits to the plasma membrane
eventOf	[Pathway:R-SPO-382556] ABC-family protein mediated transport - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-5678863] CFTR transports Cl- from cytosol to extracellular region - Schizosaccharomyces pombe [Reaction:R-SPO-383190] HCO3- transport through ion channel - Schizosaccharomyces pombe
inferredFrom	[BlackBoxEvent:R-HSA-8866851] CFTR transits to the plasma membrane - Homo sapiens
input	[DefinedSet:R-SPO-8866837-3] Homologues of CFTR [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CFTR transits to the plasma membrane
output	[DefinedSet:R-SPO-383188-3] Homologues of CFTR [plasma membrane]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-8866851
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-382556] ABC-family protein mediated transport
(precedingEvent)	[Reaction:R-SPO-5678863] CFTR transports Cl- from cytosol to extracellular region [Reaction:R-SPO-383190] HCO3- transport through ion channel
(inferredTo)	[BlackBoxEvent:R-HSA-8866851] CFTR transits to the plasma membrane

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