Reactome | RNA primer-DNA primer:origin duplex [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-SPO-68437] RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] - Schizosaccharomyces pombe
consumedByEvent	[Reaction:R-SPO-113504] Detection of damage during initiation of DNA synthesis in S-phase - Schizosaccharomyces pombe [Reaction:R-SPO-69053] RFC binding displaces Pol Alpha - Schizosaccharomyces pombe
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11051796
displayName	RNA primer-DNA primer:origin duplex [nucleoplasm]
hasComponent	[OtherEntity:R-ALL-68424] DNA primer [nucleoplasm] [Complex:R-SPO-68423] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-68425] RNA primer-DNA primer:origin duplex [nucleoplasm] - Homo sapiens
maxDepth	5
name	RNA primer-DNA primer:origin duplex
producedByEvent	[Reaction:R-SPO-68950] The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin - Schizosaccharomyces pombe
schemaClass	Complex
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-68425
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SPO-113504] Detection of damage during initiation of DNA synthesis in S-phase [Reaction:R-SPO-69053] RFC binding displaces Pol Alpha
(output)	[Reaction:R-SPO-68950] The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin
(hasComponent)	[Complex:R-SPO-68437] RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] [Complex:R-SPO-68441] RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm]
(inferredTo)	[Complex:R-HSA-68425] RNA primer-DNA primer:origin duplex [nucleoplasm]