Reactome | (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)

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(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) Show undefined attributes

catalystActivity	[CatalystActivity:11061202] nucleoside diphosphate kinase activity of NME1,2 hexamers [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11061206
displayName	(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)
eventOf	[Pathway:R-SPO-499943] Interconversion of nucleotide di- and triphosphates - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) - Homo sapiens
input	[DefinedSet:R-ALL-482625] (d)NTP [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) GTP + ADP => GDP + ATP CTP + ADP => CDP + ATP UTP + ADP => UDP + ATP dATP + ADP => dADP + ATP dGTP + ADP => dGDP + ATP dCTP + ADP => dCDP + ATP dTTP + ADP => dTDP + ATP dUTP + ADP => dUDP + ATP
output	[DefinedSet:R-ALL-482627] (d)NDP [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
precedingEvent	[Reaction:R-SPO-73647] Amination of uridine 5'-triphosphate (UTP) to form cytidine 5'-triphosphate (CTPS) - Schizosaccharomyces pombe
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-482621
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-499943] Interconversion of nucleotide di- and triphosphates
(inferredTo)	[Reaction:R-HSA-482621] (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)

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