Reactome | VEGFA-VEGFR2 Pathway

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11078923
displayName	VEGFA-VEGFR2 Pathway
eventOf	[Pathway:R-SPO-194138] Signaling by VEGF - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-SPO-5218920] VEGFR2 mediated vascular permeability - Schizosaccharomyces pombe [Pathway:R-SPO-5218921] VEGFR2 mediated cell proliferation - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-4420097] VEGFA-VEGFR2 Pathway - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	VEGFA-VEGFR2 Pathway
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-4420097
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-194138] Signaling by VEGF
(inferredTo)	[Pathway:R-HSA-4420097] VEGFA-VEGFR2 Pathway

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