Reactome | ZnT1 mediates the efflux of zinc from the cell

Schema > Reaction > Entries

ZnT1 mediates the efflux of zinc from the cell Show undefined attributes

catalystActivity	[CatalystActivity:11060627] zinc ion transmembrane transporter activity of SLC30A1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11060629
displayName	ZnT1 mediates the efflux of zinc from the cell
eventOf	[Pathway:R-SPO-435368] Zinc efflux and compartmentalization by the SLC30 family - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-435366] ZnT1 mediates the efflux of zinc from the cell - Homo sapiens
input	2 × [SimpleEntity:R-ALL-351626] H+ [extracellular region] [SimpleEntity:R-ALL-29426] Zn2+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ZnT1 mediates the efflux of zinc from the cell
output	2 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-158417] Zn2+ [extracellular region]
precedingEvent	[Reaction:R-SPO-442393] ZIP7 mediates zinc efflux from the endoplasmic reticulum - Schizosaccharomyces pombe
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-435366
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-435368] Zinc efflux and compartmentalization by the SLC30 family
(inferredTo)	[Reaction:R-HSA-435366] ZnT1 mediates the efflux of zinc from the cell

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