Reactome | FCERI mediated NF-kB activation

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11078973
displayName	FCERI mediated NF-kB activation
eventOf	[Pathway:R-SPO-2454202] Fc epsilon receptor (FCERI) signaling - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SPO-202328] Translocation of PKC theta to plasma membrane - Schizosaccharomyces pombe [Reaction:R-SPO-2730835] Autophosphorylation of PKC-theta - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-2871837] FCERI mediated NF-kB activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	FCERI mediated NF-kB activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-2871837
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-2454202] Fc epsilon receptor (FCERI) signaling
(inferredTo)	[Pathway:R-HSA-2871837] FCERI mediated NF-kB activation

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