Reactome | Generation of second messenger molecules

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11078975
displayName	Generation of second messenger molecules
eventOf	[Pathway:R-SPO-202403] TCR signaling - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SPO-202354] Translocation of PLC-gamma1 to PIP2 - Schizosaccharomyces pombe [Reaction:R-SPO-202407] PLC-gamma1 hydrolyses PIP2 - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-202433] Generation of second messenger molecules - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Generation of second messenger molecules
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-202433
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-202403] TCR signaling
(inferredTo)	[Pathway:R-HSA-202433] Generation of second messenger molecules

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