Reactome | Trimming of peptides in ER

Schema > BlackBoxEvent > Entries

Trimming of peptides in ER Show undefined attributes

catalystActivity	[CatalystActivity:11090878] endopeptidase activity of ERAP1/2 [endoplasmic reticulum lumen]
category	omitted
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11090880
displayName	Trimming of peptides in ER
eventOf	[Pathway:R-SCE-983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-983158] Trimming of peptides in ER - Homo sapiens
input	[SimpleEntity:R-ALL-983034] oligopeptide fragment [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Trimming of peptides in ER
output	[SimpleEntity:R-ALL-983033] Antigen peptide [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-8943716] L-amino acid [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-983158
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC
(inferredTo)	[BlackBoxEvent:R-HSA-983158] Trimming of peptides in ER