Reactome | SBH1:GET3:ADP binds GET1:GET2

Schema > Reaction > Entries

SBH1:GET3:ADP binds GET1:GET2 Show undefined attributes

authored	[InstanceEdit:9628624] May, Bruce, 2018-11-10
catalystActivity	[CatalystActivity:9628647] ATP hydrolysis activity of SBH1:GET3:ADP [cytosol]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9628637] May, Bruce, 2018-11-10
dbId	9628646
displayName	SBH1:GET3:ADP binds GET1:GET2
edited	[InstanceEdit:9628624] May, Bruce, 2018-11-10
input	[Complex:R-SCE-9628660] GET1:GET2 [endoplasmic reticulum membrane] [Complex:R-SCE-9628662] SBH1:GET3:ADP [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9628645] Tail-Anchored Protein Insertion by a Single Get1/2 Heterodimer [LiteratureReference:9628384] The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein insertase [LiteratureReference:9628659] The mechanism of tail-anchored protein insertion into the ER membrane [LiteratureReference:9628658] Get1 stabilizes an open dimer conformation of get3 ATPase by binding two distinct interfaces [LiteratureReference:9628644] Structural insight into the membrane insertion of tail-anchored proteins by Get3 [LiteratureReference:9628656] The GET complex mediates insertion of tail-anchored proteins into the ER membrane [LiteratureReference:9629065] Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway [LiteratureReference:9629063] Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SBH1:GET3:ADP binds GET1:GET2
orthologousEvent	[Reaction:R-HSA-9609899] Tail-anchored protein:ASNA1:ADP binds WRB:CAMLG at the endoplasmic reticulum membrane - Homo sapiens
output	[Complex:R-SCE-9628642] SBH1:GET3:ADP:GET1:GET2 [endoplasmic reticulum membrane]
releaseDate	2019-03-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9628231] DeLaurentiis, Evelina, 2018-11-07 [InstanceEdit:9628224] Farkas, �kos, 2018-11-07 [InstanceEdit:9628222] Schwappach, Blanche, 2018-11-07 [InstanceEdit:9629086] DeLaurentiis, Evelina, 2018-11-19
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-9628646
summation	[Summation:9628649] The GET3:ADP dimer bound to a tail-anchored protein interact...