Reactome | Transferrin endocytosis and recycling

Schema > Pathway > Entries

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107590
displayName	Transferrin endocytosis and recycling
eventOf	[Pathway:R-SCE-917937] Iron uptake and transport - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:263816] transferrin transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-917841] Acidification of Tf:TfR1 containing endosome - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-917977] Transferrin endocytosis and recycling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Transferrin endocytosis and recycling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-917977
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-917937] Iron uptake and transport
(inferredTo)	[Pathway:R-HSA-917977] Transferrin endocytosis and recycling

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