Reactome | Formation of MIB complex containing the MICOS complex

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Formation of MIB complex containing the MICOS complex Show undefined attributes

authored	[InstanceEdit:8953545] May, Bruce, 2016-12-23
category	omitted
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:8953620] May, Bruce, 2016-12-26
dbId	8953627
displayName	Formation of MIB complex containing the MICOS complex
edited	[InstanceEdit:8953545] May, Bruce, 2016-12-23
input	[EntityWithAccessionedSequence:R-SCE-8953643] MIC10 [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-SCE-8953597] MIC12 [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-SCE-8953638] MIC19 [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-SCE-8953655] MIC26 [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-SCE-8953649] MIC27 [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-SCE-8953640] MIC60 [mitochondrial inner membrane] [Complex:R-SCE-1252236] SAM complex [mitochondrial outer membrane] [Complex:R-SCE-1252238] TOM complex [mitochondrial outer membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8953645] Mic10 oligomerizes to bend mitochondrial inner membranes at cristae junctions [LiteratureReference:8953605] The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria [LiteratureReference:8953665] Central role of Mic10 in the mitochondrial contact site and cristae organizing system [LiteratureReference:8874896] The Oxidation Status of Mic19 Regulates MICOS Assembly [LiteratureReference:8953652] Distinct Roles of Mic12 and Mic27 in the Mitochondrial Contact Site and Cristae Organizing System [LiteratureReference:8953639] The ATP synthase is involved in generating mitochondrial cristae morphology [LiteratureReference:8953621] Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains [LiteratureReference:8953630] QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of MIB complex containing the MICOS complex
orthologousEvent	[BlackBoxEvent:R-HSA-8949609] Formation of MIB complex containing the MICOS complex causes curvature of mitochondrial inner membrane - Homo sapiens
output	[Complex:R-SCE-8953593] MIB (yeast) [mitochondrial inner membrane]
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8955549] Harper, J Wade, 2017-01-11 [InstanceEdit:8961759] Kozjak-Pavlovic, Vera, 2017-02-05
schemaClass	BlackBoxEvent
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-8953627
summation	[Summation:8953614] Assembly of the MICOS complex (MINOS complex) on the inner m...

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