Reactome | Neddylation

Schema > Pathway > Entries

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107956
displayName	Neddylation
eventOf	[Pathway:R-SCE-597592] Post-translational protein modification - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-SCE-5690808] UCHL3, SENP8 cleave NEDD8 - Saccharomyces cerevisiae [Reaction:R-SCE-8951644] Release of mature NEDD8 - Saccharomyces cerevisiae [Reaction:R-SCE-9758088] UBXN7 binds VCP hexamer:UBF1:NPLOC4 - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-8951664] Neddylation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Neddylation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-8951664
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-597592] Post-translational protein modification
(inferredTo)	[Pathway:R-HSA-8951664] Neddylation