Reactome | Release of mature NEDD8

Schema > Reaction > Entries

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11103262
displayName	Release of mature NEDD8
eventOf	[Pathway:R-SCE-8951664] Neddylation - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8951644] Release of mature NEDD8 - Homo sapiens
input	[Complex:R-SCE-6782643] UCHL3,SENP8:NEDD8 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Release of mature NEDD8
output	[EntityWithAccessionedSequence:R-SCE-416969] RUB1 [cytosol] [EntityWithAccessionedSequence:R-SCE-5690773] YUH1 [cytosol]
precedingEvent	[Reaction:R-SCE-5690808] UCHL3, SENP8 cleave NEDD8 - Saccharomyces cerevisiae
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-8951644
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-8951664] Neddylation
(inferredTo)	[Reaction:R-HSA-8951644] Release of mature NEDD8

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