Reactome | Gluconeogenesis

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Gluconeogenesis Show undefined attributes

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11106714
displayName	Gluconeogenesis
eventOf	[Pathway:R-SCE-70326] Glucose metabolism - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:15002] gluconeogenesis
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-70501] PC carboxylates PYR to OA - Saccharomyces cerevisiae [Reaction:R-SCE-70494] Enolase dimers (ENO1,2,3) convert PEP to 2PG - Saccharomyces cerevisiae [Reaction:R-SCE-71445] PGAM dimers isomerise 2PG to 3PG - Saccharomyces cerevisiae [Reaction:R-SCE-70486] PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG - Saccharomyces cerevisiae [Reaction:R-SCE-70482] GAPDH tetramers reduce 1,3BPG to GA3P - Saccharomyces cerevisiae [Reaction:R-SCE-70481] TPI1 dimer isomerizes GA3P to DHAP - Saccharomyces cerevisiae [Reaction:R-SCE-70479] FBP tetramers hydrolyze F1,6PP to Fru(6)P - Saccharomyces cerevisiae [Reaction:R-SCE-70475] GPI dimer isomerizes Fru(6)P to G6P - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-70263] Gluconeogenesis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Gluconeogenesis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-70263
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-70326] Glucose metabolism
(inferredTo)	[Pathway:R-HSA-70263] Gluconeogenesis

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