Reactome | TRM44 2'-O-methylates uridine-44 in tRNA(Ser)

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TRM44 2'-O-methylates uridine-44 in tRNA(Ser) Show undefined attributes

authored	[InstanceEdit:6788634] May, Bruce, 2015-07-23
catalystActivity	[CatalystActivity:6788679] tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity of TRM44 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6788697] May, Bruce, 2015-07-24
dbId	6788673
displayName	TRM44 2'-O-methylates uridine-44 in tRNA(Ser)
edited	[InstanceEdit:6788634] May, Bruce, 2015-07-23
goBiologicalProcess	[GO_BiologicalProcess:23385] tRNA methylation
input	[SimpleEntity:R-ALL-71284] AdoMet [cytosol] [GenomeEncodedEntity:R-SCE-6788669] tRNA(Ser) containing U-44 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6788689] Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TRM44 2'-O-methylates uridine-44 in tRNA(Ser)
orthologousEvent	[Reaction:R-HSA-6788707] TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) - Homo sapiens
output	[SimpleEntity:R-ALL-71285] AdoHcy [cytosol] [GenomeEncodedEntity:R-SCE-6788694] tRNA(Ser) containing 2'-O-methylU-44 [cytosol]
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6792690] Motorin, Yuri, 2015-08-25 [InstanceEdit:6806693] Jarrous, Nayef, 2015-10-24
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-6788673
summation	[Summation:6788681] TRM44 methylates the 2' hydroxyl group of uridine-44 in tRNA...

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