TRM44 2'-O-methylates uridine-44 in tRNA(Ser)

Stable Identifier
R-SCE-6788673
Type
Reaction [transition]
Species
Saccharomyces cerevisiae
Compartment
cytosol
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TRM44 2'-O-methylates uridine-44 in tRNA(Ser)

TRM44 methylates the 2' hydroxyl group of uridine-44 in tRNA(Ser) (Kotelawala et al. 2008). The resulting 2'-O-methyluridine-44 together with N(4)-acetylcytidine appears to be required to maintain abundance of tRNA(Ser).

Literature References
Participants
Input
Output
Event Information
Go Biological Process
tRNA methylation (0030488)
Catalyst Activity
Catalyst Activity
Title
tRNA (uracil-2'-O-)-methyltransferase activity of TRM44 [cytosol]
Physical Entity
TRM44 [cytosol]
Activity
tRNA (uracil-2'-O-)-methyltransferase activity (0052665)
Orthologous Events
TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) (Homo sapiens)
Authored
May, B  (2015-07-23)
Reviewed
Motorin, Y  (2015-08-25)
Jarrous, N  (2015-10-24)
Created
May, B  (2015-07-24)
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