Reactome | RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:11095868] protein serine/threonine kinase activity of RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-SCE-5623667] PDPK1 phosphorylates PKN1,2,3 - Saccharomyces cerevisiae
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11095854
displayName	RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane]
hasComponent	[Complex:R-SCE-109697] PDPK1:PIP3 [plasma membrane] [Complex:R-SCE-5623624] RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-5623637] RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] - Homo sapiens
maxDepth	6
name	RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3
producedByEvent	[Reaction:R-SCE-5623632] RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 - Saccharomyces cerevisiae
schemaClass	Complex
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-5623637
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SCE-5623667] PDPK1 phosphorylates PKN1,2,3
(physicalEntity)	[CatalystActivity:11095868] protein serine/threonine kinase activity of RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane]
(output)	[Reaction:R-SCE-5623632] RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3
(inferredTo)	[Complex:R-HSA-5623637] RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane]

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