Reactome | PAN2-PAN3 complex partially deadenylates mRNA

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PAN2-PAN3 complex partially deadenylates mRNA Show undefined attributes

catalystActivity	[CatalystActivity:11088956] poly(A)-specific ribonuclease activity of PAN2-PAN3 Complex [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11088958
displayName	PAN2-PAN3 complex partially deadenylates mRNA
eventOf	[Pathway:R-SCE-429947] Deadenylation of mRNA - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-430021] PAN2-PAN3 complex partially deadenylates mRNA - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-SCE-429977] Translatable mRNA Complex [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PAN2-PAN3 complex partially deadenylates mRNA
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [Complex:R-SCE-429989] Partially Deadenylated mRNA Complex [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-430021
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-429947] Deadenylation of mRNA
(inferredTo)	[Reaction:R-HSA-430021] PAN2-PAN3 complex partially deadenylates mRNA

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